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Most doctors recommend seeking medical attention if a low-grade fever is present for more than two days. If a person’s fever spikes or goes above 100 degrees Fahrenheit, they should be seen immediately. A low-grade fever is a sign that the body is fighting off an infection or virus. When a fever spikes it indicates something is going on that the body is having trouble bringing under control. This could mean a bad virus or something else that could lead to serious health issues. While a fever’s main purpose is to create an environment where viruses cannot thrive, carrying a fever for longer than two to three days may cause other health issues, such as dehydration or a decreased metabolism.